Recurrent implantation failure treatment | Expert 101

As some of us here at the HQ TRB know it too well, going through IVF takes a huge amount of energy, time and inner strength.

So, when an embryo transfer does not work, we generally wanted an explanation, as well as clear advice for what to do next, right?

But if this happens more than once, you can hear your doctor mention recurring implantation failure, or rif. It is difficult, often a deeply emotional reality, and it can let you ask “Why me?” or even, “Do I do something wrong?”

Recurrent implantation failure treatment – it is possible

The first thing to know is this – ” It’s never your fault. The establishment is complicated and influenced by many factors, which is why one of the best things you can do is to draw on the advice of experienced specialists who can assess your situation and recommend the next tailor -made steps.

For this type of super specific support, we turn to The prelude network® – The largest and fastest network of fertility clinics in the United States and Canada. We have confirmed and demystified after the symptoms of daily embryos transfer, as well as the recurrent processing options unpacked with their team of experts, so do them in a bookmark if you are already.

With Dr. Michael Strug, breeding endocrinologist and fertility specialist in Pacific Fertility Center®We explain the most effective recurring implantation failure processing options available today and walking step by step in their approach.

To Dr Strug.

Recurrent implantation problems Definition of IVF

Most fertility specialists define a recurring implantation failure as Three or more faults of failing embryos involving embryos which have been confirmed as genetically normalL (EUPOIDE) through pre -implantation genetic tests.

However, the RIF can be difficult to define with precision, as individual factors such as overall health or other medical conditions may affect the chances of implantation.

Treatment begins with the understanding of the causes of failure of the recurring implementation

So, what causes a recurring failure of the establishment? In an frustrating way, in most cases, there are no clearly identifiable causes, which probably reflect factors of embryos or uterus for which we do not have a test currently.

That said, when I try to understand the recurring causes of the failure of the establishment, I start by looking at three main areas:

1. Lifestyle factors – These include things like diet, exercise and avoid harmful substances. For example, improving nutrition and reducing alcohol or tobacco can help improve the quality of eggs and sperm, which can increase the chances of success.
2. Medical conditions “Some health problems, such as obesity or autoimmune disorders that are not well managed, can make an embryo more difficult to set up. Tacking and optimizing these medical conditions before trying another embryo transfer can improve the chances.”
3. Fertility treatment specifics – Sometimes the way in which a patient’s body responds during treatment can affect the implantation. A common problem is when the uterus lining (called the endometrium) is too thin or does not have the ideal model for implantation.
   In these cases, we can adjust the drug used to prepare the lining, or recommend surgical procedures to study the mucosa and the uterine cavity more closely. »»

Tests and diagnoses to ask questions about

Then I will watch Review all your previous cyclesincluding the creation and transfer of embryos. This can help us highlight the egg, sperm or uterus factors to improve before the next attempt.

Recommended current checks include:

• Thyroid and diabetes price If it is not done recently.
• Caryotype blood test To look at the health of chromosomes.
• Anti-phospholid antibody testBecause these antibodies can interfere with the location.
• Hysteroscopy To see the uterus directly and take a sample from the mucosa to test chronic endometrite (low level inflammation).

Most of the time, these tests come back normal. But if something is found, there are specific treatments that can help improve the chances of successful pregnancy.

Recurrent implantation failure treatment – Options based on evidence

Because, as I mentioned, the failure processing of the recurring implantation depends on the cause (or the suspected cause), I will often start by ensuring that overall health and the medical conditions that could affect the establishment are well managed.

From there, we then look:

• Optimization of overall health “Managing weight and improving nutrition can help.
• Improve the quality of eggs and sperm – Lifestyle changes and certain supplements can help.
• Improve the uterine lining – If it is too thin, drug protocols can be adjusted to encourage better growth.
• Approach uterine anomalies – Polyps, scar tissues or other problems can be deleted surgically.
• Treat chronic endometrite – Antibiotics followed by a retest can confirm that the infection has been erased.
• Manage anti-phospholipid antibodies – Anticoagulants can be recommended.

What you can control – first -rate pointers

Because there are so many things that will not be under your control here, it can be useful to focus on this East. Here are my three main pointers for patients who sail on a recurring implantation failure: ”

1. Be informed “Do not hesitate to ask questions of your care team. Understand what could cause implantation problems and what can be done to help you give you more clarity and control during the process.
2. Focus on your health – Your overall health plays a big role in fertility. Eating a balanced and remaining diet can support both your general well-being and your reproductive health.
3. Be careful with unproven treatments – Certain treatments, in particular those intended for the immune system, are marketed with people with the RIF. However, many of them are not supported by solid research and could even be risky. It is important to follow the advice based on evidence of fertility specialists in trust.

Your mental health is also important

It is a really important part of treatment. Feeling uncontrollable is incredibly frustrating and can wreak havoc on your emotional well-being.

To help manage this stress, many people find activities such as exercise or meditation useful, as they can stimulate natural endorphins and improve mood.

It has also been shown that practicing mindfulness reduces stress, anxiety and depression, and I would recommend useful applications like Timer And Head spacewhich offer guided meditation and relaxation exercises.

Should you keep trying? Fonde line

The answer is that it depends on your situation. IVF treatment can be unpredictable and embryos transfers do not always succeed during the first attempts.

Research shows that TRUE The failure of the recurring implementation is rare, with approximately 92% of people getting pregnant after three transfers of or more embryos.

My principal to remember? Although repeated failing transfers can be one of the most difficult experiences during the treatment of fertility and we often do not find confirmed causes, it is never your fault, and it is not at the end of the road with the right tests, a tailor -made plan and the support of a qualified care team that are willing to try different options.

The Prelude Network® brings together leading fertility clinics in the United States and Canada, offering advanced diagnostics, compassion care and recurring implantation failure treatment options to give you the best possible opportunities for success.

Want to discuss what your options might look like? Find your closest clinic here.