Expert analyzes potential new breakthrough in pancreatic cancer
Revolution Medicines this week announced a stunning survival benefit for its investigational drug in a phase 3 study in pancreatic cancer.
Patients with advanced pancreatic adenocarcinoma who were treated with the company’s daily pill called daraxonrasib lived a median of 13.2 months, compared with 6.7 months for patients who received standard chemotherapy.
Revolution said it plans to use the data to seek approval from the Food and Drug Administration, although it did not say when. When he submits the data, approval can be quick.
STAT spoke with Paul Oberstein of NYU Langone’s Perlmutter Cancer Center, an investigator on the trial, on his biotech podcast “The Readout Loud.”
This transcript has been lightly edited for length and clarity.
Let’s start by talking about pancreatic cancer in general. Why is it so difficult to treat and what are the current survival rates?
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